Kev npaj Piperidine

Nws yog tsim los ntawm catalytic hydrogenation ntawm pyridine. Cov pyridine thiab nickel catalyst tau ntxiv rau hauv autoclave, thiab hydrogen ntxiv thaum nws tau rhuab mus rau 50 degree C, thiab hydrogen txuas ntxiv mus rau 200 degree C, thiab hydrogen siab yog ze li ntawm 7MPa thiab tsis absorbs hydrogen. Cov kua tshuaj tiv thaiv yog lim, cov lim dej yog fractionated, thiab cov kua distilled tau sau ntawm 102-108 degree kom tau piperidine. Lwm txoj kev npaj yog muab pyridine nyob rau hauv anhydrous ethanol, kub nws, muab sodium hlau rau hauv nws, tom qab cov tshuaj tiv thaiv lawm, siv chav distillation mus rau chav piperidine thiab ethanol, neutralize nrog hydrochloric acid thiab chav ethanol kom tau piperidine hydrochloride, thiab kho. nrog sodium hydroxide kom tau txais piperidine dawb.