REDOX Reaction Ntawm Pyridine

Vim qhov tsawg ntom ntom ntawm cov huab cua ntawm lub nplhaib pyridine, feem ntau tsis yooj yim rau oxidized, tshwj xeeb tshaj yog nyob rau hauv acidic tej yam kev mob, tom qab ntsev ntawm pyridine, nitrogen atom muaj ib tug zoo nqi, thiab induction nyhuv ntawm electron nqus. ntxiv dag zog rau, kom cov huab cua electron ceev ntawm lub nplhaib yog qis dua, thiab kev ruaj ntseg ntawm oxidizer yog nce. Thaum lub nplhaib pyridine muaj ib sab saw, sab saw oxidation tshwm sim.
Nyob rau hauv tshwj xeeb oxidation tej yam kev mob, pyridine tuaj yeem raug oxidation cov tshuaj tiv thaiv zoo ib yam li tertiary amine los tsim N-oxide. Piv txwv li, thaum pyridine cuam tshuam nrog peroxic acid lossis hydrogen peroxide, pyridine n-oxide tau txais.
Pyridine n-oxide tuaj yeem txo kom deoxygenate. Nyob rau hauv pyridine n-oxide, lub unshared electron khub ntawm cov pa atom yuav conjugated nrog cov aromatic loj π daim ntawv cog lus, uas ua rau kom lub electron huab ceev ntawm lub nplhaib, thiab cov chaw thiab qhov chaw nce ho, uas ua rau lub pyridine nplhaib electrophilic hloov cov tshuaj tiv thaiv. yooj yim tshwm sim. Vim tias qhov txiaj ntsig zoo ntawm cov nitrogen atom tom qab tsim cov pyridine n-oxide, qhov cuam tshuam ntawm kev nqus hluav taws xob nce, kom cov hluav taws xob huab cua ceev ntawm txoj hauj lwm raug txo, yog li cov tshuaj tiv thaiv electrophilic hloov feem ntau tshwm sim ntawm 4 (). Nyob rau tib lub sijhawm, pyridine n-oxide kuj muaj feem cuam tshuam rau kev hloov pauv nucleophilic.
Nyob rau hauv sib piv rau oxidation cov tshuaj tiv thaiv, pyridine yog nquag hydrogenation txo ntawm benzene nplhaib, uas yuav txo tau los ntawm catalytic hydrogenation thiab tshuaj reagents.